Jessica Holmes
Executive Head of Market Access

Jeffrey Sirek
CEO, Board Member

Tonya Dowd
Jessica Holmes

Jessica’s function at PRIA Healthcare:

In her role at PRIA, Jessica leads market access strategy with a rare blend of analytical precision and strategic creativity, helping medical technology companies anticipate reimbursement challenges and design clear, executable pathways to sustainable adoption. She partners closely with cross-functional leaders to translate clinical and regulatory innovation into real-world evidence strategies, coverage frameworks, and coding and payment outcomes that support successful commercialization. Jessica’s work brings clarity to complexity, aligning policy, data and market dynamics to enable informed decision-making across the product lifecycle.


A senior market access and reimbursement executive with more than 25 years of experience advising medical technology companies on U.S. healthcare policy and payment strategy, she has led reimbursement planning and execution across the full product lifecycle, guiding organizations through evidence development, coverage, coding and payment pathways to support commercialization and long-term adoption.


Jessica's life before joining the People of PRIA Healthcare:

Prior to joining PRIA, Jessica founded and led Regency Market Access Consulting, where she advised emerging and established companies on reimbursement readiness, payer engagement, and access risk management. Prior consulting leadership roles include Director of Life Sciences at Navigant Consulting (now Guidehouse) and Vice President of Reimbursement at Argenta Advisors (now PRIA). She has also held numerous senior in-house roles, including Vice President of Health Policy & Reimbursement at Neuspera Medical, and Vice President of Market Access at Sight Sciences, supporting both pre-commercial and publicly traded organizations.



Jessica’s life outside of PRIA Healthcare:

Outside of work, Jessica enjoys family, friends, painting, traveling, and finding recipes on YouTube that don’t include cottage cheese.

Jessica’s full bio:

Jessica is a senior market access and reimbursement strategist with more than 25 years of experience helping medical technology companies navigate the U.S. healthcare system and achieve sustainable market adoption. She specializes in designing and executing actionable reimbursement strategies and tactical plans that integrate clinical evidence, regulatory planning, and payer requirements to support successful commercialization across medical devices, diagnostics, digital health and biotechnology. 


In her role at PRIA, Jessica leads market access strategy with a rare blend of analytical precision and strategic creativity, helping medical technology companies anticipate reimbursement challenges and design clear, executable pathways to sustainable adoption. She partners closely with cross-functional leaders to translate clinical and regulatory innovation into real-world evidence strategies, coverage frameworks, and coding and payment outcomes that support successful commercialization. Jessica’s work brings clarity to complexity, aligning policy, data and market dynamics to enable informed decision-making across the product lifecycle.


Prior to joining PRIA, Jessica founded and led Regency Market Access Consulting, where she advised emerging and established companies on reimbursement readiness, payer engagement, and access risk management. Prior consulting leadership roles include Director of Life Sciences at Navigant Consulting (now Guidehouse) and Vice President of Reimbursement at Argenta Advisors (now PRIA). She has also held numerous senior in-house roles, including Vice President of Health Policy & Reimbursement at Neuspera Medical, and Vice President of Market Access at Sight Sciences, supporting both pre-commercial and publicly traded organizations.


In addition to her work in-house and as an external consultant, Jessica is a recognized educator and thought leader in the med-tech ecosystem, frequently serving as a lecturer and advisor to academic, industry and government organizations. Such institutions include Stanford Biodesign, UC Davis Innovation and Venture Catalyst programs, Fogarty Innovation (FI), and California Life Sciences (CLS), in addition to several foreign government programs supporting their countries’ respective medical technology initiatives. Her work is grounded in a pragmatic understanding of how policy, evidence and market access mechanics shape real-world adoption, and how to design strategies that endure.


Jessica holds a Master of Jurisprudence in Health Law from Loyola University Chicago School of Law, a Bachelor of Arts in Mass Communications from the University of California at Berkeley, and a certification in Disruptive Strategy from Harvard Business School.